Turner's syndrome: diagnosis and management with limited resources

Turner Syndrome or Bonnevie-Ulrich syndrome is a syndrome of gonadal dysgenesis characterized by sexual infantilism, short stature and somatic anomalies. These case reports are meant not only to describe the clinical features of Turners syndrome but also illustrate the challenges faced in the bid to diagnose this medical condition with the available limited diagnostic tools

scope o f cardiac complications of thyrotoxicosis in Lagos, Nigeria

One of the main complications of thyrotoxicosis [TS] is heart disease, including heart rhythm abnormalities. There is a dearth of reports from sub-saharan Africa hence this study sets out to bridge this gap This was a prospective study carried out for a 24 months period. All subjects with clinical and or biochemical evidence of TS, were followed up and examined for clinical and laboratory features of cardiac complications of thyrotoxicosis. A total of 103 subjects with TS were seen thus giving an incidence rate of 27%. The Male: Female ratio of the subjects with thyrocardiac disease was 1:5 Frequency of hypertension, arrhythmias and heart failure were 53%, 25% and 42% respectively. Subjects with cardiac complications of TS had florid clinical features of thyrotoxicosis. Echcocardiographic features documented in some of the subjects with heart failure include dilated heart wall, impaired systolic function, reduced ejection fraction and fractional shortening. Thyrotoxicosis is a notable cause of cardiac morbidity in Nigerians